This is, probably, going to be the best DreamWorks Animations film since Madagascar and before that Shrek (which recently opened a Broadway musical. Go figure.).
The story, according to Wikipedia:
"When California resident Susan Murphy mysteriously grows to 49 ft 11 in, on her wedding day, she is labelled a monster and taken in by the military to a institution housing other monsters, such as Dr. Cockroach, Ph.D., an insect-headed mad scientist, the Missing Link, a thousands-of-years-old fish-man, B.O.B., an indestructible gelatinous mass and Insectosaurus, a fuzzy bug that makes even Susan look tiny by comparison. When a UFO lands and aliens demand that Earth be given to them, General W.R. Monger suggests to the President that the monsters can provide the firepower to defeat the aliens."
The all-star cast includes -
Reese Witherspoon as Susan Murphy / Ginormica
Paul Rudd as Derek
Hugh Laurie as Dr. Cockroach, Ph.D.
Will Arnett as The Missing Link
Seth Rogen as B.O.B.
Kiefer Sutherland as Gen. W.R. Monger
Stephen Colbert as The President of the United States
Rainn Wilson as Gallaxhar